SARS-CoV-2 (501.V2) Stabilized Spike Glycoprotein (Full-Length), His-Strep-Tag (HEK293)
商品詳細
Product Code | REC31926-100 |
---|---|
Product Name | SARS-CoV-2 (501.V2) Stabilized Spike Glycoprotein (Full-Length), His-Strep-Tag (HEK293) |
Product Description | SARS-CoV-2 HexaPro stabilized Spike glycoprotein containing amino acid changes in accordance with variant 501.V2 (“South African variant”): D80A, D215G, K417N, E484K, N501Y, A701V relative to Wuhan-Hu-1. This protein has the polybasic furin cleavage site “RRAR” changed to “SRAS” to prevent furin cleavage of the target protein. The protein also contains 6 amino acid changes to proline and a C-terminal T4 fibritin trimerization domain to stabilize the protein in its pre-fusion conformation as described in Hsieh, Goldsmith et al. 2020. The protein was produced in HEK293 and purified from culture supernatant. |
Product Sub-Group | Recombinant Antigen |
Inactivation method | |
Strain | 501.V2 |
Concentration (mg/ml) | 0.92 |
Purity (%) | >90 |
Presentation | Liquid |
Vial Size mg | 0.1 |
Preservative | |
Product URL | |
Clone Number | |
Immunogen | |
Tag | His-Tag, 2 x Strep-Tag |
Tag Terminus | C-terminus |
Linker | GSGGSGGGS |
Molecular Weight (kDa) | 139 |
References | |
SHIPPING CONDITIONS | DRY ICE |
Short-Term Storage Temperature (°C) | -80 |
Long-Term Storage Temperature (°C) | -80 |
Freezing | Can be frozen |
Storage Guidelines | Avoid multiple freeze/thaw cycles. |
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