SARS-CoV-2 (B.1.1.7) Stabilized Spike Glycoprotein, His-Strep-Tag (HEK293)
商品詳細
| Product Code | REC31924-500 |
|---|---|
| Product Name | SARS-CoV-2 (B.1.1.7) Stabilized Spike Glycoprotein, His-Strep-Tag (HEK293) |
| Product Description | SARS-CoV-2 HexaPro stabilized Spike glycoprotein containing deletions and amino acid changes in accordance with variant B.1.1.7 (“UK variant”): 69-70del, Y144del, N501Y, A570D, P681H, T716I, S982A, D1118H relative to Wuhan-Hu-1. The polybasic furin cleavage site was changed from “RRAR” to “GSAS” to prevent cleavage of the protein during production. This protein contains 6 amino acid changes to proline and a C-terminal T4 fibritin trimerization domain to stabilize the protein in its pre-fusion conformation as described in Hsieh, Goldsmith et al. 2020. The protein was produced in HEK293 and purified from culture upernatant. |
| Product Sub-Group | Recombinant Antigen |
| Inactivation method | |
| Strain | B.1.1.7 |
| Concentration (mg/ml) | 0.61 |
| Purity (%) | >95 |
| Presentation | Liquid |
| Vial Size mg | 0.5 |
| Preservative | |
| Product URL | |
| Clone Number | |
| Immunogen | |
| Tag | His-Tag, 2 x Strep-Tag |
| Tag Terminus | C-terminus |
| Linker | GSGGSGGGS |
| Molecular Weight (kDa) | 139 |
| References | |
| SHIPPING CONDITIONS | DRY ICE |
| Short-Term Storage Temperature (°C) | -80 |
| Long-Term Storage Temperature (°C) | -80 |
| Freezing | yes |
| Storage Guidelines | Avoid repeated freeze/thaw cycles. |
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